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Roximately 15% of the body's heme, but the majority is produced in the bone marrow. Heme produced in the liver is primarily used to produce cytochromes and peroxisomes, and heme produced in the bone marrow is primarily used for hemoglobin synthesis and oxygen transport. As demonstrated in the following image,. buy viagra without prescription F a collection of pct studies noted hepatitis c infection in 50% of documented cases of pct. Additional risk factors include alcohol abuse, excess iron, and exposure to chlorinated cyclic hydrocarbons and agent orange. It can be a paraneoplastic phenomenon. [7] [edit] exacerbating factors alcohol [8] estrogen iron [9] [edit] pathogenesis as stated previously, porphyria cutanea tarda is primarily caused by uroporphyrinogen decarboxylase deficiency (urod). Uroporphyrinogen decarboxylase o.